M.von der ThusenJ
In the case of multiple melanotic macules, the following rare genetic conditions may be involved: Laugier-Hunziker syndrome Carney complex LEOPARD syndrome Peutz-Jeghers syndrome LAMB syndrome NAME syndrome It is important to note that having a risk factor does not mean that one will get the condition
Recognised side effects that require medical attention include severe abdominal pain (which could indicate pancreatitis), persistent nausea and vomiting leading to dehydration, signs of gallbladder problems such as jaundice or right upper abdominal pain, changes in vision (especially if you have type 2 diabetes with pre-existing diabetic retinopathy), or symptoms of hypoglycaemia if you are taking other diabetes medications
For example, seaweed-derived components can modulate gut microbiota by altering the Firmicutes/Bacteroidetes ratio and increasing the abundance of beneficial bacteria like Bacteroides and Lactobacillus 44,45
Severe adverse reactions included serious gastrointestinal disorders, hepatobiliary disorders, gallbladder disorders, and mild acute pancreatitis